Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814
- Creator: Walweel, Kafa , Gomez-Hurtado, Nieves , Laver, Derek R. , Rebbeck, Robyn T. , Oo, Ye Wint , Beard, Nicole A. , Molenaar, Peter , dos Remedios, Chris , van Helden, Dirk F. , Cornea, Razvan L. , Knollmann, Björn C.
- Resource Type: journal article
- Date: 2019
Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants
- Creator: Hwang, Hyun Seok , Nitu, Florentin R. , Cornea, Razvan L. , Bers, Donald M. , Knollmann, Björn C. , Yang, Yi , Walweel, Kafa , Pereira, Laetitia , Johnson, Christopher N. , Faggioni, Michela , Chazin, Walter J. , Laver, Derek , George Jr, Alfred L.
- Resource Type: journal article
- Date: 2014
Inhibition of cardiac Ca²⁺ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia
- Creator: Hwang, Hyun Seok , Hasdemir, Can , Laver, Derek , Mehra, Divya , Turhan, Kutsal , Faggioni, Michela , Yin, Huiyong , Knollmann, Björn C.
- Resource Type: journal article
- Date: 2011
Flecainide inhibits arrhythmogenic Ca²⁺ waves by open state block of ryanodine receptor Ca²⁺ release channels and reduction of Ca²⁺ spark mass
- Creator: Hilliard, Fredrick A. , Steele, Derek S. , Laver, Derek , Yang, Zhaokang , Le Marchand, Sylvain J. , Chopra, Nagesh , Piston, David W. , Huke, Sabine , Knollmann, Björn C.
- Resource Type: journal article
- Date: 2010
Amitriptyline activates cardiac ryanodine channels and causes spontaneous sarcoplasmic reticulum calcium release
- Creator: Chopra, Nagesh , Laver, Derek , Davies, Sean S. , Knollmann, Björn C.
- Resource Type: journal article
- Date: 2009
Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans
- Creator: Watanabe, Hiroshi , Chopra, Nagesh , Laver, Derek , Hwang, Hyun Seok , Davies, Sean S. , Roach, Daniel E. , Duff, Henry J. , Roden, Dan M. , Wilde, Arthur A. M. , Knollmann, Björn C.
- Resource Type: journal article
- Date: 2009